Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years. Hundreds of labs around the world are now working to put these tools to clinical use and are ...

本研究针对CRISPR-Cas系统在微生物基因交换中的双重作用机制这一科学问题，开展了CRISPR-Cas靶向对嗜盐古菌Haloferax volcanii种内接合影响的主题研究。研究人员通过精确的基因编辑构建靶向菌株，结合接合实验、Cas3基因敲除和DNA损伤处理等实验，发现CRISPR-Cas靶向可 ...

本综述系统梳理了CRISPR-Cas系统在双歧杆菌中的分布规律，并重点评述了基于内源与外源CRISPR-Cas系统的基因组编辑工具的开发与应用现状。文章深入探讨了双歧杆菌基因编辑面临的关键挑战（如低转化效率、菌株差异性），并展望了大型基因片段插入、原位编辑 ...

In the second new research review on this subject, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, ...

This is a preview. Log in through your library . Abstract CRISPR/Cas9 technology has immense power to reproduce plants with desired characters and revolutionizing the field of genome engineering by ...

The discovery of CRISPR-Cas gene editing technology has revolutionized biological research, providing new insights and opportunities for the advancement of several industries. However, the ...

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Different kinds of chromosome segment inversions have been found in ...

Researchers uncovered a previously unknown CRISPR immune response in bacteria that targets transfer RNAs. The newly ...

Co-authored by Sheena Wang and Ellie Purnell of HGF limited, “CRISPR and Agriculture” was originally published by Food and Drink Technology on January 29, 2025. To access the article on the Food and ...

Genetic modifications in reproductive cells, such as eggs, sperm, or embryos, are commonly referred to as germline editing and are heritable. 1 CRISPR-Cas 9, which stands for clustered regularly ...